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Bestsellers

Blue Copper 5® Firming Elasticity Repair

For crepey, sagging, slack skin

$86.00

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Blue Copper 5 PRIME® Face Cream

For deep lines & lost firmness 40+

$129.00

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Under Eye Rejuvenator

For dark circles & puffiness

$120.00

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Blue Copper 5 PRIME® Eye Cream

For hooded lids & crow's feet

$120.00

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Nécolleté Age Reversal for Neck and Chest

For a crepey, lined neck & chest

$84.00

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Blue Copper 5 PRIME® Sleep Tight Mask

For overnight firming & lines

$120.00

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Environmental Age Defense Moisture Cloud

For dehydrated, stressed skin

$86.00

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Lipofill Skin Firmness Restoration

For lost facial volume & folds

$120.00

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Cream Extreme Intensive Repair

For very dry, dehydrated skin

$86.00

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Blue Copper 5® Firming Elasticity Repair\ Copper peptide regenerative firming cream with Matrixyl® 3000 — for crepey, sagging skin and lost firmness\ $86.00](/content/products/blue-copper-5-firming-elasticity-repair-1/index.html) Blue Copper 5 PRIME® Face Cream\ Copper peptide face cream with Matrixyl® 3000, Pentavitin® & complete barrier-lipid complex — for deep lines, sagging jowls, lost firmness and comfort dryness in skin 40+\ $129.00](/content/products/blue-copper-5-prime-face/index.html) Under Eye Rejuvenator\ Copper peptide eye cream with Eyeseryl® & Haloxyl™ — for stubborn dark circles, puffiness and crepey lids\ $120.00](/content/products/under-eye-rejuvenator/index.html) Blue Copper 5 PRIME® Eye Cream\ Copper peptide eye cream with Matrixyl® 3000 — restorative for wrinkles, crow's feet and hooded lids\ $120.00](/content/products/blue-copper-5-prime-eye-1/index.html)

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Osmotics — Anti-Aging Copper Peptide Skincare

Pioneers of Copper-Peptide Science · Since 1998

The science of copper. The art of ageless skin.

In 1998 we created the world's first Blue Copper firming treatment. Today, Blue Copper 5® — the first penta-peptide copper molecule — visibly firms, lifts and smooths.

Shop PRIME Face Find your routine

The Hero Cream

Collagen-boosting peptides, at their full clinical dose.

Not a trace added for the label — the whole studied concentration, the same strength used in the placebo-controlled research behind the ingredient.

Shop Firming Elasticity Repair Find your routine

Eyes

Eye peptides, dosed at clinical strength.

For puffiness, dark circles and the tired look that no amount of sleep seems to fix — with peptides carried at the concentration used in the research behind them.

Shop Under Eye Rejuvenator Find your routine

Lips

Needle-free plumping, powered by hyaluronic acid.

Fuller, smoother, better-defined lips without a syringe — built on a hyaluronic complex clinically shown to add visible lip volume.

Shop Lip Plumper Find your routine

01 / 04

Dermatologist

Recommended

Copper Peptide

Technology

Scientific

Advisory Panel

Made in

the USA

4.8★ · 12,000+

Reviews

Dermatologist

Recommended

Copper Peptide

Technology

Scientific

Advisory Panel

Made in

the USA

4.8★ · 12,000+

Reviews

Dermatologist

Recommended

Copper Peptide

Technology

Scientific

Advisory Panel

Made in

the USA

4.8★ · 12,000+

Reviews

As Featured In

Bestsellers

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★★★★★4.9 · 1061 reviewsBlue Copper 5® Firming Elasticity Repair\ Copper peptide regenerative firming cream with Matrixyl® 3000 — for crepey, sagging skin and lost firmness](/content/products/blue-copper-5-firming-elasticity-repair-1/index.html)

1.7 oz1.0 oz8.0 oz$86.00

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★★★★★5.0 · 224 reviewsBlue Copper 5 PRIME® Face Cream\ Copper peptide face cream with Matrixyl® 3000, Pentavitin® & complete barrier-lipid complex — for deep lines, sagging jowls, lost firmness and comfort dryness in skin 40+](/content/products/blue-copper-5-prime-face/index.html)

1.7 oz$129.00

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★★★★★5.0 · 408 reviewsUnder Eye Rejuvenator\ Copper peptide eye cream with Eyeseryl® & Haloxyl™ — for stubborn dark circles, puffiness and crepey lids](/content/products/under-eye-rejuvenator/index.html)

0.5 oz$120.00

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★★★★★5.0 · 120 reviewsBlue Copper 5 PRIME® Eye Cream\ Copper peptide eye cream with Matrixyl® 3000 — restorative for wrinkles, crow's feet and hooded lids](/content/products/blue-copper-5-prime-eye-1/index.html)

0.5 fl oz$120.00

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★★★★★5.0 · 144 reviewsNécolleté Age Reversal for Neck and Chest\ Peptide neck & chest cream with Essenskin® & Chromocare® — firms crepey skin and evens redness & sun discoloration below the jaw](/content/products/necollete-age-reversal-for-neck-and-chest-1/index.html)

1.7 oz$84.00

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★★★★★5.0 · 154 reviewsBlue Copper 5 PRIME® Sleep Tight Mask\ Copper peptide overnight firming mask — Chrono-Active Repair for dry, thinning skin that looks flat on waking](/content/products/blue-copper-5-prime-sleep-tight-mask-1/index.html)

1.7 oz$120.00

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★★★★★5.0 · 59 reviewsEnvironmental Age Defense Moisture Cloud\ Ceramide & squalane barrier cream that combats all 3 free-radical types — for dehydrated, reactive skin exposed to pollution & blue light](/content/products/environmental-age-defense-moisture-cloud-1/index.html)

1.7 oz$86.00

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★★★★★5.0 · 51 reviewsLipofill Skin Firmness Restoration\ Needle-free peptide serum — for nasolabial folds, lost facial volume and crepey, slackening skin](/content/products/lipofill-volume-enhancing-filler/index.html)

1.7 oz$120.00

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★★★★★4.9 · 72 reviewsCream Extreme Intensive Repair\ Rich ceramide barrier & lipid repair cream — for parched, stressed skin with a broken moisture barrier](/content/products/cream-extreme-intensive-repair-1/index.html)

1.7 oz$86.00

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Common Concerns

Not sure where to begin? Here are some common skin concerns — pick yours and we’ll match you to the right copper-peptide treatment.

Fine Lines & Wrinkles](/content/collections/fine-lines-wrinkles/index.html) Loss of Firmness](/content/collections/loss-of-firmness/index.html) Dark Circles & Puffiness](/content/collections/dark-circles-puffiness/index.html) Dark Spots & Uneven Tone](/content/collections/dark-spots-uneven-tone/index.html) Dryness & Dehydration](/content/collections/dryness-dehydration/index.html) Crepey Neck & Chest](/content/collections/crepey-neck-chest/index.html)

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Browse the full range — from targeted serums and eye care to cleansers, masks and body care.

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Serums](/content/collections/serums/index.html) Creams & Moisturizers](/content/collections/creams-moisturizers/index.html) Eye Care](/content/collections/eye-care/index.html) Cleansers & Toners](/content/collections/cleansers-toners/index.html) Masks & Treatments](/content/collections/masks-treatments/index.html) Complexion & Glow](/content/collections/complexion-glow/index.html) Body & Bath](/content/collections/body-bath/index.html)

Clinically Proven

Results you can measure

Real people. Real results. Every Osmotics hero is built on clinically studied actives, dosed at the levels used in the research — never fairy-dusted.

PRIME FaceFirming Elasticity RepairUnder Eye RejuvenatorPRIME EyeSleep Tight MaskLipofillMoisture CloudBody LiftLip PlumperNécolleté

BeforeAfter 8 weeks

BeforeAfter 8 weeks

Photography of an individual user following twice-daily use for 8 weeks. Individual results vary.

Blue Copper 5 PRIME Face

Our most advanced copper-peptide cream — collagen-boosting peptides above their studied strength

$129.00

Add to Bag$129.00

In just 8 weeks*:

96%

of participants saw firmer, lifted skin

96%

saw a visible reduction in fine lines

94%

said their skin felt more hydrated

100%

said their skin looked more youthful

*Consumer perception study. Individual results vary. The ingredient-level evidence — including the exact peptides and the doses they are carried at — is published in full on the product evidence page.

Discover More

See the full science behind PRIME Face

BeforeAfter 8 weeks

BeforeAfter 8 weeks

Photography of an individual user following twice-daily use for 8 weeks. Individual results vary.

Blue Copper 5 Firming Elasticity Repair

The hero cream — collagen-boosting peptides at their full clinical dose

$86.00

Add to Bag$86.00

In just 8 weeks*:

95%

saw firmer, more elastic skin

94%

saw a visible reduction in wrinkles

92%

said their skin felt more supple

100%

said their skin looked more youthful

*Consumer perception study. Individual results vary. Ingredient-level clinical evidence for the collagen-boosting peptides, and the dose they are carried at, is published on the product evidence page.

Discover More

See the peptide clinical data

BeforeAfter 4 weeks

BeforeAfter 4 weeks

Photography of an individual user following twice-daily use for 4 weeks. Individual results vary.

Under Eye Rejuvenator

Eye peptides at double their clinically studied strength

$120.00

Add to Bag$120.00

In just 4 weeks*:

98%

saw reduced under-eye puffiness

98%

saw brighter under-eyes

98%

said dark circles looked reduced

100%

said their eye area looked more rested

*Consumer perception study. Individual results vary. Ingredient-level clinical evidence for the eye peptides is published on the product evidence page.

Discover More

See the eye-peptide clinical data

BeforeAfter 4 weeks

BeforeAfter 4 weeks

Photography of an individual user following twice-daily use for 4 weeks. Individual results vary.

Blue Copper 5 PRIME Eye

Multi-peptide eye cream — lift, crow’s feet, dark circles and bags

$120.00

Add to Bag$120.00

In just 4 weeks*:

94%

saw a lifted, firmer eye area

94%

saw reduced crow’s feet

96%

said dark circles looked reduced

100%

said their eyes looked more awake

*Consumer perception study. Individual results vary. PRIME Eye’s full peptide stack is dose-confirmed — see the evidence page.

Discover More

See the confirmed peptide doses

BeforeAfter 4 weeks

BeforeAfter 4 weeks

Photography of an individual user following nightly use for 4 weeks. Individual results vary.

Blue Copper 5 PRIME Sleep Tight Mask

Overnight volumising mask — copper peptide with volumising peptides at their studied dose

$120.00

Add to Bag$120.00

In just 4 weeks*:

98%

saw plumper, more rested skin on waking

96%

saw a fuller, more cushioned complexion

96%

said their skin felt more hydrated

100%

would recommend it

*Consumer perception study. Individual results vary. Ingredient-level evidence for the volumising peptide at its studied dose is published on the product evidence page.

Discover More

See the volume data

BeforeAfter 8 weeks

BeforeAfter 8 weeks

Photography of an individual user following twice-daily use for 8 weeks. Individual results vary.

Lipofill Skin Firmness Restoration

Anti-gravity firming serum — firming peptides at their full studied dose

$120.00

Add to Bag$120.00

In just 8 weeks*:

92%

saw firmer, more lifted skin

94%

saw a visible reduction in nasolabial lines

96%

said their facial contour looked tighter

99%

would recommend it

*Consumer perception study. Individual results vary. Ingredient-level evidence for the firming peptide at its studied dose is published on the product evidence page.

Discover More

See the firmness data

BeforeAfter 4 weeks

BeforeAfter 4 weeks

Photography of an individual user following twice-daily use for 4 weeks. Individual results vary.

Environmental Age Defense Moisture Cloud

Barrier-repair moisturiser — ceramides, phytosterols and an anti-glycation peptide

$86.00

Add to Bag$86.00

In just 4 weeks*:

98%

said their skin felt less dry and tight

96%

saw a calmer, less reactive complexion

96%

said their skin barrier felt stronger

98%

would recommend it

*Consumer perception study. Individual results vary. The ingredient evidence for this formula is in vitro — measured in cell cultures, not on volunteers — and is published in full, clearly labelled, on the product evidence page.

Discover More

See the barrier-lipid data

BeforeAfter 8 weeks

BeforeAfter 8 weeks

Photography of an individual user following twice-daily use for 8 weeks. Individual results vary.

Blue Copper 5 Anti-Aging Body Lift

Firming peptides at their clinical dose — for stretch marks and crepey skin

$139.00

Add to Bag$139.00

In just 8 weeks*:

94%

saw smoother, firmer body skin

98%

saw improved stretch-mark appearance

94%

said skin felt more elastic

100%

would recommend it

*Consumer perception study. Individual results vary. Ingredient-level clinical evidence for the firming peptide is published on the product evidence page.

Discover More

See the firming clinical data

BeforeAfter 4 weeks

BeforeAfter 4 weeks

Photography of an individual user following twice-daily use for 4 weeks. Individual results vary.

Blue Copper 5 Lip Plumper

Needle-free hyaluronic plumping, clinically shown to add lip volume

$74.00

Add to Bag$74.00

In just 4 weeks*:

98%

saw fuller, plumper lips

96%

said lips felt more hydrated

96%

saw smoother lip texture

100%

would recommend it

*Consumer perception study. Individual results vary. Ingredient-level clinical evidence for the hyaluronic lip complex is published on the product evidence page.

Discover More

See the lip-volume clinical data

BeforeAfter 8 weeks

BeforeAfter 8 weeks

Photography of an individual user following twice-daily use for 8 weeks. Individual results vary.

Nécolleté Age Reversal for Neck and Chest

Firming peptides for the neck and chest — the area a face routine forgets

$84.00

Add to Bag$84.00

In just 8 weeks*:

91%

said skin looked visibly tightened

90%

said it felt more moisturised

*Consumer perception study. Individual results vary. Ingredient-level clinical evidence for the firming peptide is published on the product evidence page.

Discover More

See the firming clinical data

Hear From Our Community

See All Reviews

In Their Words

Awesome

I am two month’s shy of 73. I have been using Blue Copper for decades. Everyone guesses my age as 50 years old! Thank you, thank you, thank you Osmotics.

Joyce B Lanham, Osmotics Customer

Blue Copper 5® Firming Elasticity Repair

Copper peptide regenerative firming cream with Matrixyl® 3000 — for crepey, sagging skin and lost firmness

Add to Bag$86.00

Blue Copper is the best!

Of all the cosmeceuticals Blue Copper is my favorite. It makes me feel luxurious plus it works.

Bonnie Schaffer, Osmotics Customer

Blue Copper 5 PRIME® Face Cream

Copper peptide face cream with Matrixyl® 3000, Pentavitin® & complete barrier-lipid complex — for deep lines, sagging jowls, lost firmness and comfort dryness in skin 40+

Add to Bag$129.00

Under eye rejuvenator

Love this product!! I have been using it for more than 20 years!!

Sue Ellen Jones, Osmotics Customer

Under Eye Rejuvenator

Copper peptide eye cream with Eyeseryl® & Haloxyl™ — for stubborn dark circles, puffiness and crepey lids

Add to Bag$120.00

A favorite repeat purchase

Put it on before bed at night and wake up with plump and youthful lips. Less lines make lips look fuller. Use as a glosser over lip pencil or even lipstick during the day too.

Elle Clever, Osmotics Customer

Blue Copper 5® Lip Plumper

Needle-free copper peptide lip plumper with hyaluronic acid — for thinning lips and lines around the mouth

Add to Bag$74.00

Sets & Regimens

Curated value sets — or build a complete four-step routine around your skin.

Flagship Set

Copper peptide Luxury Collection

The ultimate anti-aging ritual — copper-peptide care for face, body, eyes and lips.

$425.00 $528.00

Add to Bag

Regimen

Face Set Collection

A full-face, science-backed regimen for smoother, firmer, younger-looking skin.

$305.00 $380.00

Add to Bag

Gift Set

Beauty Face Collection

A compact, giftable edit of lip, eye and serum essentials for ageless radiance.

$219.00 $272.00

Add to Bag

Night Ritual

Sleep Tight Collection

Overnight restoration that lifts, hydrates and renews while you sleep.

$219.00 $270.00

Add to Bag

Eye Ritual

Eye Set Collection

Depuff, brighten and firm the delicate eye area for a rested, wide-awake gaze.

$199.00 $248.00

Add to Bag

Your routine, in four steps.

Answer a few questions about your skin and goals, and we'll assemble a complete Cleanse · Treat · Boost · Support routine.

CleanseTreatBoostSupport

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The Vault

The first cult formulas returning to the line — a longevity serum, an exfoliator and a facial oil among them. Join the waitlist to be first.

↓  Tap “Notify me” on any formula to join its waitlist

Returning first

R+R Longevity Serum

Renovage + Retinol cellular-longevity serum.

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Returning first

Renovage Longevity Serum

Teprenone cellular-longevity treatment.

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Returning first

Instant Exfoliating Facial

Copper-peptide exfoliating facial.

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Returning first

Skin Nourishing Oil

A nourishing multi-oil facial blend.

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Returning first

Dark Spot Remover

Targeted brightening with 3% alpha arbutin.

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Loyalty, Rewarded With The Osmotics Hub

Join the Osmotics community to earn rewards while you care for your skin. The more you shop, the faster your points build — all while treating your skin to the best of Blue Copper 5.

See member benefits

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Silver12×$300+ a year

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On the record since 1993

As Seen On — Long Before Skincare Had Influencers

Back when TV came in one size (large and beige), Osmotics and our patented Blue Copper 5® were already making national headlines. FOX, CNN, NBC and more put our breakthroughs on air — and yes, the footage is gloriously grainy. That’s not a bad connection; that’s three decades of receipts. Grab the remote and press play.

Fox NewsNational TV feature

CNNNational TV feature

Oscar BuzzNational TV feature

NBCNational TV feature

Fox 31National TV feature

Filmed in the age of tube TVs and dial-up — kept exactly as aired, pixels and all. The clips got older; the science only got better.

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Skincare Resources

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Osmotics Journal28 Sep 2026Sensitive Skin & Redness: How to Calm, Strengthen and Soothe ItSensitive skin and redness explained — why skin becomes reactive (usually a compromised barrier), what triggers flushing, and the ceramides, niacinamide, hyaluronic acid and...\ Read Now Osmotics Journal28 Sep 2026Dark Spots & Uneven Skin Tone: What Causes Them and How to Fade ThemDark spots and uneven skin tone explained — the real causes (sun, post-acne marks, melasma, slow turnover), how the types differ, and the vitamin...\ Read Now Osmotics Journal28 Sep 2026Thinning Lips & Lip Lines: How to Plump and Smooth Them Without FillerThinning lips and lip lines explained — why lips lose volume and definition and vertical “smoker’s lines” form with age, and the peptides, hyaluronic...\ Read Now Osmotics Journal28 Sep 2026Crepey Skin on the Body: What Causes It and How to Firm & Smooth the LookCrepey skin on the body — thin, finely wrinkled skin on the arms, chest, knees and hands — explained: what causes it, why the...\ Read Now 19 Sep 2026Fine Lines: What Causes Them and How to Soften the LookFine lines explained — how dehydration lines differ from early wrinkles, why they form, and the hyaluronic acid, peptides, retinol and SPF habits that...\ Read Now](/content/blogs/news/fine-lines-what-causes-them-and-how-to-soften-the-look/index.html) 19 Sep 2026Crepey Neck and Chest: What Causes It and How to Smooth the LookThe neck and décolletage age faster than the face. Here's why the skin there turns crepey and slack, how to tell crepiness from wrinkles,...\ Read Now](/content/blogs/news/crepey-neck-and-chest-what-causes-it-and-how-to-smooth-the-look/index.html) 19 Sep 2026Loss of Firmness: Why Skin Starts to Sag and How to Firm the LookWhy skin loses firmness with age — collagen and elastin decline, shifting fat pads and sun damage — plus the copper peptides, retinol and...\ Read Now](/content/blogs/news/loss-of-firmness-why-skin-starts-to-sag-and-how-to-firm-the-look/index.html) 18 Sep 2026Nasolabial Folds: What Causes Them and How to Soften the LookNasolabial folds — the lines from nose to mouth — explained: what causes smile lines to deepen, how to tell whether yours are from...\ Read Now](/content/blogs/news/nasolabial-folds-causes-treatment/index.html) 06 Sep 2026The Science of Copper Peptides: How Osmotics Skincare Actually WorksHow copper peptides support the look of firmness, elasticity and renewal — and which Osmotics product does each job. A science-backed guide to the...\ Read Now](/content/blogs/news/the-science-of-copper-peptides-how-osmotics-skincare-actually-works/index.html) 21 Aug 2026The Skin Barrier & Hydration Guide: How to Repair, Strengthen and Deeply Hydrate Your SkinWhat the skin barrier is, why it breaks down, and exactly how to repair and deeply hydrate it — with ceramides, barrier lipids, hyaluronic...\ Read Now](/content/blogs/news/skin-barrier-hydration-guide/index.html) 12 Aug 2026Dark Circles and Under-Eye Bags: What Causes Them and How to Treat the LookDark circles and puffy under-eye bags explained — the three types, what causes them, and the science-backed ingredients and habits that actually improve the...\ Read Now](/content/blogs/news/dark-circles-under-eye-bags-causes-treatment/index.html) 06 Aug 2026Copper Peptides for Skin Over 40: Firmer, Smoother, More Resilient SkinAfter 40, skin looks less firm and fine lines start to settle in. Here's why copper peptides suit mature skin — and how to...\ Read Now](/content/blogs/news/copper-peptides-for-skin-over-40/index.html)

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